Sulbactam-ampicillin associated hepatocellular type liver injury
| Journal | Volume 75 - 2012 |
| Issue | Fasc.1 - Letters |
| Author(s) | Aydın ş. Köksal, Hakan Yıldız, Oğuz önder, Sedat Avcı, Ertuğrul Kayaçetin |
| Full article |
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| (1) Department of Gastroenterology and (2) Cardiology, Türkiye Yüksek Ihtisas Hospital. |
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Drug induced liver disease accounts for up to 10% of all adverse drug reactions. Drugs account for 2-5% of cases of patients hospitalized with jaundice and up to 30% of patients who present with acute hepatitis (1-3). The clinical presentation varies widely and can mimic acute and chronic liver diseases. Severity of toxic- hepatitis varies from non-specific changes to fulminant hepatic failure and cirrhosis. Early detection is important because it can decrease the severity of hepatotoxicity if the drug is discontinued. |
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© Acta Gastro-Enterologica Belgica. PMID 22567755 |
